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Christian Seiser Selected Research

Histone Deacetylase 1

1/2021Histone deacetylase 1 controls CD4+ T cell trafficking in autoinflammatory diseases.
1/2020Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis.
12/2010Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans.
9/2010Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production.
7/2007Role for histone deacetylase 1 in human tumor cell proliferation.
4/2003The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene.

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Christian Seiser Research Topics

Disease

11Neoplasms (Cancer)
11/2021 - 04/2003
3Carcinogenesis
01/2021 - 01/2011
2Inflammation (Inflammations)
11/2021 - 09/2010
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2021 - 01/2018
2Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked)
11/2020 - 01/2020
1Bites and Stings (Sting)
11/2021
1Lymphoma (Lymphomas)
01/2021
1Brain Diseases (Brain Disorder)
11/2020
1Multiple Sclerosis
11/2020
1Neuroinflammatory Diseases
11/2020
1Arthritis (Polyarthritis)
01/2020
1Experimental Arthritis
01/2020
1Demyelinating Diseases (Demyelinating Disease)
01/2020
1Schizophrenia (Dementia Praecox)
01/2018
1Breast Neoplasms (Breast Cancer)
12/2013
1Neural Tube Defects (Exencephaly)
01/2013
1Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
01/2011
1Teratoma (Teratoid Tumor)
12/2010

Drug/Important Bio-Agent (IBA)

10Histone Deacetylase InhibitorsIBA
01/2020 - 04/2003
6Histone Deacetylase 1IBA
01/2021 - 04/2003
5Histone Deacetylases (Histone Deacetylase)IBA
11/2020 - 12/2010
2DNA (Deoxyribonucleic Acid)IBA
11/2021 - 01/2021
2VorinostatFDA Link
01/2020 - 01/2011
2EnzymesIBA
01/2017 - 02/2011
2Cyclin-Dependent Kinase Inhibitor p21IBA
12/2010 - 04/2003
2Antineoplastic Agents (Antineoplastics)IBA
03/2010 - 04/2003
1Anaplastic Lymphoma KinaseIBA
01/2021
1MethyltransferasesIBA
01/2021
1entinostat (MS 275)IBA
11/2020
1LipidsIBA
11/2020
1Fatty Acids (Saturated Fatty Acids)IBA
11/2020
1Histones (Histone)IBA
11/2020
1Collagen Type II (Type II Collagen)IBA
01/2020
1Protein Isoforms (Isoforms)IBA
10/2018
1CannabinoidsIBA
01/2018
1AM 251 (AM251)IBA
01/2018
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
12/2013
1Ligases (Synthetase)IBA
12/2013
1trichostatin A (A 300)IBA
01/2013
1theasinensin AIBA
01/2013
1romidepsin (FK228)FDA Link
01/2011
1DepsipeptidesIBA
01/2011
1Indicators and Reagents (Reagents)IBA
12/2010
1CytokinesIBA
09/2010
1Proteins (Proteins, Gene)FDA Link
07/2007
1Sp1 Transcription FactorIBA
04/2003

Therapy/Procedure

2Therapeutics
02/2011 - 01/2011
1Immunotherapy
11/2021
1Hematopoietic Stem Cell Transplantation
01/2020